When you install Outlook, an Inbox repair tool (scanpst.exe) is also installed on your PC. The Inbox repair tool can resolve problems by scanning your Outlook data files, and repairing errors. To use the Inbox repair tool, exit Outlook, and then follow the steps in Repair Outlook Data Files (.pst and .ost). As your mailbox size increases, more resources are required to open each folder. If you have a large number of items in any single folder, you may experience performance issues during certain operations.
Find solutions to common problems or get help from troubleshooting Outlook startup issues a support agent. If Outlook is NOT able to start in safe mode, then try the next proposed solution below, entitled Create a new Outlook profile. Outlook may be running with settings meant for an older Windows version. For more detailed instruction on how to enable or disable add-ins see this Quick Tip.If you you get an error that you cannot disable the add-in see this Quick Tip instead. The "Cannot open the Outlook window" error can be fixed quite easily. If you share this computer with another user, you can ask this other user to logon and ask to verify if Outlook is still working for him or her.
It seems like something went wrong on Microsoft update and they might recall it or fix it, so we might need to wait untill that. We have multiple tools to help you automatically troubleshooting Outlook startup issues diagnose an issue, troubleshoot, and fix problems with Outlook. If you can't open Outlook, or Outlook disappears or crashes, one of your add-ins may be to blame or you may need to update Outlook. The navigation pane is the leftmost pane in Outlook where you'll find your folder list and the icons to move between Mail, Calendar, People, and Tasks.
Uninstalling this part of your virus scanner is strongly advised